Diurnal variability of C-reactive protein in obstructive sleep apnea

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Elevated C-Reactive Protein in Patients With Obstructive Sleep Apnea

Background—Obstructive sleep apnea (OSA) has been increasingly linked to cardiovascular and cerebrovascular disease. Inflammatory processes associated with OSA may contribute to cardiovascular morbidity in these patients. We tested the hypothesis that OSA patients have increased plasma C-reactive protein (CRP). Methods and Results—We studied 22 patients (18 males and 4 females) with newly diagn...

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Obesity has emerged as one of the most important epidemics in the western hemisphere, and as its prevalence continues to increase in children, the associated risk for cardiovascular and metabolic complications follows parallel increases in prevalence, and reflects activation of underlying inflammatory pathways. The obstructive sleep apnea syndrome (OSAS) is a frequent condition in children asso...

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Is C-reactive protein a marker of obstructive sleep apnea?

BACKGROUND Obstructive sleep apnea (OSA) is a common disease, distinguished by recurrent episodes of upper airway obstruction during sleep, with an inflammatory component. C-reactive protein (CRP) and high-sensitivity C-reactive protein (hs-CRP) are markers of systemic inflammation and may serve as biomarkers of OSA. METHODS Scientific studies published from January 1, 2006, to January 1, 201...

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Altered cardiovascular variability in obstructive sleep apnea.

BACKGROUND Altered cardiovascular variability is a prognostic indicator for cardiovascular events. Patients with obstructive sleep apnea (OSA) are at an increased risk for cardiovascular disease. We tested the hypothesis that OSA is accompanied by alterations in cardiovascular variability, even in the absence of overt cardiovascular disease. METHODS AND RESULTS Spectral analysis of variabilit...

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Impact of mandibular advancement devices on C-reactive protein levels in patients with obstructive sleep apnea.

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ژورنال

عنوان ژورنال: Sleep and Breathing

سال: 2009

ISSN: 1520-9512,1522-1709

DOI: 10.1007/s11325-009-0268-0